Study Site Descriptions

There are two fields associated with the program:

Iquitos, Peru

Iquitos NASA

Iquitos

Evaluation of the ability of spatial repellents to prevent infection with dengue virus is being conducted in Iquitos, Peru. Iquitos is located northeast of Lima along the tributaries of the Amazonian river and is only accessible by plane or boat. The population of the city is over 422,000 inhabitants, making it the biggest city in the world which is inaccessible by road. 

All four dengue virus serotypes have circulated in Iquitos and dengue fever occurs routinely in the population. Dengue epidemis have caused severe health burden in many years. We have selected 26 clusters, each comprising approximately 180 homes, from within Iquitos to participate in the trial.

The Housing

The houses in Iquitos are typically made out of wood or cement for walls and metal for roofs. Often times individual homes share walls with adjacent houses and therefore open spaces exists at the eaves.

View of Iquitos, Peru

Street in Iquitos, Peru

Inside of a house in Iquitos

The Iquitos, Peru Spatial Repellent Study Team

Dr. Thomas Scott and Dr. Amy Morrison, both of the Department of Entomology and Nematology, at UC Davis, in California USA are the Principal Investigators of the Iquitos trial and oversee field teams conducting both human and mosquito sampling. They are partnering with the U.S. Naval Medical Research Unit 6, Virology laboratory in Lima, Peru for serological testing and virus isolation.

Dr. Thomas W Scott from UC Davis

Dr. Thomas W. Scott is known for his holistic and comprehensive approach in finding solutions to protect the world's population from dengue. He has researched mosquito-borne disease for 35 years, is a global authority on the epidemiology of mosquito-borne disease, mosquito ecology, evolution of mosquito-virus interactions, and evaluation of novel products and strategies for mosquito control and disease prevention. For more information.

Amy Morrison from UC Davis

Dr. Amy Morrison has focused her research efforts on dengue since 1994. as been a member of Dr. Thomas Scott’s laboratory since the fall of 1996 and has served as the Field Director for all research activities on dengue epidemiology and Aedes aegypti ecology at the Amazonian field site in Iquitos, Peru.  In addition to these duties, Amy Morrison, Ph.D. serves as the Director of the Naval Medical Research Center Detachment (NMRCD) Iquitos Laboratory and is stationed in Iquitos full-time. For more information.

 

Sumba Island, Indonesia

Evaluation of the ability of a spatial repellent to prevent infection with malaria parasites is being conducted on Sumba Island, Indonesia.

sumba_island

Sumba Island is a member of the Lesser Sunda Archipelago, located in East Nusa Tenggara Province, Indonesia. The island is divided into 4 districts or regency, West Sumba, East Sumba, Central Sumba and Southwest Sumba. Sumba has an area of 11,153 km2, and the population was 685,186 in 2010. 

Sumba Island is classified as a hypo to meso endemic malaria area with perennial malaria transmission. We have selected 12 villages in the West Sumba and South West Sumba districts, totaling approximately 2,500 homes, for the trial. 

 

The Housing

The houses on Sumba Island are typically made out of bamboo for walls and floors with dried palm leaves (thatch) used for roofs. Often times homes are raised above the ground with animal pens underneath.

Village on the Sumba Island

House is the Sumba Island

Inside of a house with a metal roof in the Sumba Island

 

The Sumba Island, Indonesia Spatial Repellent Study Team

Dr. Din Syafruddin from the Eijkman Institute

Dr. Din Syafruddin, of the Eijkman Institute for Molecular Biology, Jarkata, Indonesia is the Principal Investigator of the Sumba Island trial and oversees field teams conducting both human and mosquito sampling. Dr. Syafruddin's research is focused on molecular biology of the energy transducing membrane of the malaria parasite, molecular mechanisms underlying Plasmodium resistance to antimalarial drugs and m olecular taxonomy of the parasite based on the mitochondrial DNA sequence. For more information.

The Sumba team:

indonesian_team